Tropism of Varicella-Zoster Virus for Human Tonsillar CD4(+) T Lymphocytes That Express Activation, Memory, and Skin Homing Markers

Varicella-zoster virus (VZV) is an alphaherpesvirus with the characteristic neurotropism of this group, but VZV also infects T cells productively and downregulates major histocompatibility complex (MHC) class I expression on infected T cells, as shown in the SCID-hu mouse model. T-cell tropism is li...

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Bibliografiska uppgifter
Huvudupphovsmän: Ku, Chia-Chi, Padilla, Jorge A., Grose, Charles, Butcher, Eugene C., Arvin, Ann M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC136789/
https://ncbi.nlm.nih.gov/pubmed/12388703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11425-11433.2002
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