Promoter Sequences of Varicella-Zoster Virus Glycoprotein I Targeted by Cellular Transactivating Factors Sp1 and USF Determine Virulence in Skin and T Cells in SCIDhu Mice In Vivo

Varicella-zoster virus (VZV) glycoprotein I is dispensable in cell culture but necessary for infection of human skin and T cells in SCIDhu mice in vivo. The gI promoter contains an activating upstream sequence that binds the cellular transactivators specificity factor 1 (Sp1) and upstream stimulator...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Ito, Hideki, Sommer, Marvin H., Zerboni, Leigh, He, Hongying, Boucaud, Dwayne, Hay, John, Ruyechan, William, Arvin, Ann M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.489-498.2003
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