Isolation and Molecular Characterization of a Nelfinavir (NFV)-Resistant Human Immunodeficiency Virus Type 1 That Exhibits NFV-Dependent Enhancement of Replication

During the use of a phenotypic anti-human immunodeficiency virus type 1 (HIV-1) drug resistance assay in a large set of clinical virus isolates, we found a unique variant (CL-4) that exhibited a high level of nelfinavir (NFV) resistance and rather enhanced replication under subinhibitory concentrati...

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Detalhes bibliográficos
Main Authors: Matsuoka-Aizawa, Saori, Sato, Hironori, Hachiya, Atsuko, Tsuchiya, Kiyoto, Takebe, Yutaka, Gatanaga, Hiroyuki, Kimura, Satoshi, Oka, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140576/
https://ncbi.nlm.nih.gov/pubmed/12477837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.318-327.2003
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