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Preferential hydrolysis of gap and bulge sites in DNA by Ce(IV)/EDTA complex

A new strategy for site-selective DNA hydrolysis, which takes advantage of the difference in reactivity between the phosphodiester linkages at the target site and the others, is presented. As the molecular scissors, homogeneous Ce(IV)/ethylenediamine-N,N,N′,N′-tetraacetate (EDTA) complex is used wit...

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kitamura, Yoshihito, Komiyama, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12364619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf101
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