Preferential hydrolysis of gap and bulge sites in DNA by Ce(IV)/EDTA complex
A new strategy for site-selective DNA hydrolysis, which takes advantage of the difference in reactivity between the phosphodiester linkages at the target site and the others, is presented. As the molecular scissors, homogeneous Ce(IV)/ethylenediamine-N,N,N′,N′-tetraacetate (EDTA) complex is used wit...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12364619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf101 |
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