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Apoptotic surface delivery of K(+) channels

Apoptosis in cortical neurons requires efflux of cytoplasmic potassium mediated by a surge in Kv2.1 channel activity. Pharmacological blockade or molecular disruption of these channels in neurons prevents apoptotic cell death, while ectopic expression of Kv2.1 channels promotes apoptosis in non-neur...

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Detalles Bibliográficos
Main Authors: Pal, SK, Takimoto, K, Aizenman, E, Levitan, ES
Formato: Artigo
Idioma:Inglês
Publicado: 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403161/
https://ncbi.nlm.nih.gov/pubmed/16273079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4401792
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