CRM1/Ran-Mediated Nuclear Export of p27(Kip1) Involves a Nuclear Export Signal and Links p27 Export and Proteolysis

We show that p27 localization is cell cycle regulated and we suggest that active CRM1/RanGTP-mediated nuclear export of p27 may be linked to cytoplasmic p27 proteolysis in early G1. p27 is nuclear in G0 and early G1 and appears transiently in the cytoplasm at the G1/S transition. Association of p27...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Connor, Michael K., Kotchetkov, Rouslan, Cariou, Sandrine, Resch, Ansgar, Lupetti, Rafaella, Beniston, Richard G., Melchior, Frauke, Hengst, Ludger, Slingerland, Joyce M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2003
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC140238/
https://ncbi.nlm.nih.gov/pubmed/12529437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-06-0319
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk