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Phase I study of intermittent and chronomodulated oral therapy with capecitabine in patients with advanced and/or metastatic cancer

BACKGROUND: The combination of capecitabine and gemcitabine at Fixed Dose Rate (FDR) has been demonstrated to be well tolerated, with apparent efficacy in patients with advanced cancers. FDR gemcitabine infusion leads to enhanced intracellular accumulation of drug and possible augmented clinical eff...

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書誌詳細
主要な著者: Santini, Daniele, Vincenzi, Bruno, Schiavon, Gaia, La Cesa, Annalisa, Gasparro, Simona, Vincenzi, Angelo, Tonini, Giuseppe
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402306/
https://ncbi.nlm.nih.gov/pubmed/16504126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-42
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