Number of active transcription factor binding sites is essential for the Hes7 oscillator

BACKGROUND: It is commonly accepted that embryonic segmentation of vertebrates is regulated by a segmentation clock, which is induced by the cycling genes Hes1 and Hes7. Their products form dimers that bind to the regulatory regions and thereby repress the transcription of their own encoding genes....

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Dettagli Bibliografici
Autori principali: Zeiser, Stefan, Liebscher, H Volkmar, Tiedemann, Hendrik, Rubio-Aliaga, Isabel, Przemeck, Gerhard KH, de Angelis, Martin Hrabé, Winkler, Gerhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402261/
https://ncbi.nlm.nih.gov/pubmed/16504083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-3-11
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