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Number of active transcription factor binding sites is essential for the Hes7 oscillator

BACKGROUND: It is commonly accepted that embryonic segmentation of vertebrates is regulated by a segmentation clock, which is induced by the cycling genes Hes1 and Hes7. Their products form dimers that bind to the regulatory regions and thereby repress the transcription of their own encoding genes....

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Detalhes bibliográficos
Main Authors: Zeiser, Stefan, Liebscher, H Volkmar, Tiedemann, Hendrik, Rubio-Aliaga, Isabel, Przemeck, Gerhard KH, de Angelis, Martin Hrabé, Winkler, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402261/
https://ncbi.nlm.nih.gov/pubmed/16504083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-3-11
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