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Pharmacokinetics of phenytoin in children.

1 Apparent Vmax and Km for phenytoin were estimated in 40 children (aged 8--33 months) and 21 adults (aged 18--66 years). 2 The derived values of Vmax and Km were used to predict the plasma and salivary concentrations of phenytoin following a change in dose. There was a highly significant correlatio...

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Bibliografske podrobnosti
Main Authors: Blain, P G, Mucklow, J C, Bacon, C J, Rawlins, M D
Format: Artigo
Jezik:Inglês
Izdano: 1981
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401952/
https://ncbi.nlm.nih.gov/pubmed/7332730
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