Oral phenytoin pharmacokinetics during omeprazole therapy.

1. In a double-blind crossover study 10 healthy males received either placebo or omeprazole (40 mg day-1) for 9 days, a single dose of phenytoin (300 mg) being taken on the seventh day. 2. Omeprazole significantly increased the area under the curve (0 to 72 h) of phenytoin (mean +/- s.e. mean) from...

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Autores principales: Prichard, P J, Walt, R P, Kitchingman, G K, Somerville, K W, Langman, M J, Williams, J, Richens, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386318/
https://ncbi.nlm.nih.gov/pubmed/3689634
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