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Pharmacokinetic investigation of the interaction of azapropazone with phenytoin.

We have investigated the interaction of azapropazone with phenytoin in five healthy volunteers. From steady-state plasma phenytoin concentrations of about 17 mumol/l there was at least a two-fold increase following the introduction of azapropazone. The main mechanism of the interaction was a decreas...

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Autors principals: Geaney, D P, Carver, J G, Davies, C L, Aronson, J K
Format: Artigo
Idioma:Inglês
Publicat: 1983
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427929/
https://ncbi.nlm.nih.gov/pubmed/6871071
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