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Structure-based design of a dimeric RNA–peptide complex
The arginine-rich RNA-binding domain of bovine immunodeficiency virus (BIV) Tat adopts a β-hairpin conformation upon binding to the major groove of BIV TAR. Based on its NMR structure, we modeled dimeric arrangements in which two adjacent TAR sites might be recognized with high affinity by a dimeric...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140190/ https://ncbi.nlm.nih.gov/pubmed/11226168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.1.178 |
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