Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility

Telomerase contains two essential components: an RNA molecule that templates telomeric repeat synthesis and a catalytic protein component. Human telomerase is processive, while the mouse enzyme has much lower processivity. We have identified nucleotide determinants in the telomerase RNA that are res...

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Pubblicato in:	EMBO J
Autori principali:	Chen, Jiunn-Liang, Greider, Carol W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12514136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg024
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