Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
Telomerase contains two essential components: an RNA molecule that templates telomeric repeat synthesis and a catalytic protein component. Human telomerase is processive, while the mouse enzyme has much lower processivity. We have identified nucleotide determinants in the telomerase RNA that are res...
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| Udgivet i: | EMBO J |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12514136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg024 |
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