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Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
Telomerase contains two essential components: an RNA molecule that templates telomeric repeat synthesis and a catalytic protein component. Human telomerase is processive, while the mouse enzyme has much lower processivity. We have identified nucleotide determinants in the telomerase RNA that are res...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140099/ https://ncbi.nlm.nih.gov/pubmed/12514136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg024 |
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