Loading...
Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor
Protective protein/cathepsin A (PPCA) has a serine carboxypeptidase activity of unknown physiological function. We now demonstrate that this protease activity triggers the degradation of the lysosome-associated membrane protein type 2a (lamp2a), a receptor for chaperone-mediated autophagy (CMA). Deg...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140041/ https://ncbi.nlm.nih.gov/pubmed/12505983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg002 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|