Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin
Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor containing an inducibly expressed HIF-1α subunit and a constititutively expressed HIF-1β subunit. Under hypoxic conditions, the HIF-1α subunit accumulates due to a decrease in the rate of proteolytic degradation, and the resu...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242281/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.7004-7014.2002 |
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