Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin

Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor containing an inducibly expressed HIF-1α subunit and a constititutively expressed HIF-1β subunit. Under hypoxic conditions, the HIF-1α subunit accumulates due to a decrease in the rate of proteolytic degradation, and the resu...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Hudson, Christine C., Liu, Mei, Chiang, Gary G., Otterness, Diane M., Loomis, Dawn C., Kaper, Fiona, Giaccia, Amato J., Abraham, Robert T.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2002
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242281/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.7004-7014.2002
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