TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins

We demonstrate that transformation-transactivation domain-associated protein (TRRAP) binding and the recruitment of histone H3 and H4 acetyltransferase activities are required for the transactivation of a silent telomerase reverse transcriptase (TERT) gene in exponentially growing human fibroblasts...

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Autors principals: Nikiforov, Mikhail A., Chandriani, Sanjay, Park, Jeonghyeon, Kotenko, Iulia, Matheos, Dina, Johnsson, Anna, McMahon, Steven B., Cole, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC139788/
https://ncbi.nlm.nih.gov/pubmed/12077335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.14.5054-5063.2002
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