Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice

BACKGROUND: Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in the interstitium resulting in respiratory failure. The role of remodeling mediators such as metalloproteinases (MMPs) and their inhibitors (TIMPs) in the fibrogenic process remains misunderstood. In pa...

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Detalhes bibliográficos
Main Authors: Manoury, Boris, Nenan, Soazig, Guenon, Isabelle, Boichot, Elisabeth, Planquois, Jean-Michel, Bertrand, Claude P, Lagente, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1397817/
https://ncbi.nlm.nih.gov/pubmed/16504062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-3-2
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