CUL-4A Is Critical for Early Embryonic Development

Ubiquitin-mediated degradation targets cell cycle regulators for proteolysis. Much of the ubiquitin pathway's substrate specificity is conferred by E3 ubiquitin ligases, and cullins are core components of some E3s. CUL-4A encodes one of six mammalian cullins and is amplified and/or overexpressed in...

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Bibliografiset tiedot
Julkaisussa:	Mol Cell Biol
Päätekijät:	Li, Binghui, Ruiz, Joseph C., Chun, Kristin T.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2002
Aiheet:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12077329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.14.4997-5005.2002
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CUL-4A Is Critical for Early Embryonic Development

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