CUL-4A Is Critical for Early Embryonic Development
Ubiquitin-mediated degradation targets cell cycle regulators for proteolysis. Much of the ubiquitin pathway's substrate specificity is conferred by E3 ubiquitin ligases, and cullins are core components of some E3s. CUL-4A encodes one of six mammalian cullins and is amplified and/or overexpressed in...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12077329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.14.4997-5005.2002 |
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