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Role of Translation Initiation Factor 2B in Control of Cell Survival by the Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3β Signaling Pathway

The phosphatidylinositol 3-kinase (PI 3-kinase)/Akt signaling pathway is an important mediator of growth factor-dependent survival of mammalian cells. A variety of targets of the Akt protein kinase have been implicated in cell survival, including the protein kinase glycogen synthase kinase 3β (GSK-3...

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Detalhes bibliográficos
Main Authors: Pap, Marianna, Cooper, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139729/
https://ncbi.nlm.nih.gov/pubmed/11756553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.578-586.2002
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