Reovirus Delays Diabetes Onset but Does Not Prevent Insulitis in Nonobese Diabetic Mice

Mice infected with reovirus develop abnormalities in glucose homeostasis. Reovirus strain type 3 Abney (T3A) was capable of systemic infection of nonobese diabetic (NOD) mice, an experimental model of autoimmune diabetes. Reovirus antigen was detected in pancreatic islets of T3A-infected mice, and p...

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Auteurs principaux: Wetzel, J. Denise, Barton, Erik S., Chappell, James D., Baer, Geoffrey S., Mochow-Grundy, Michelle, Rodgers, Steven E., Shyr, Yu, Powers, Alvin C., Thomas, James W., Dermody, Terence S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395416/
https://ncbi.nlm.nih.gov/pubmed/16501117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.6.3078-3082.2006
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