The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

Dnmt3L is required for the establishment of maternal methylation imprints at imprinting centers (ICs). Dnmt3L, however, lacks the conserved catalytic domain common to DNA methyltransferases. In an attempt to define its function, we coexpressed DNMT3L with each of the two known de novo methyltransfer...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chédin, Frédéric, Lieber, Michael R., Hsieh, Chih-Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12481029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262443999
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