The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a
Dnmt3L is required for the establishment of maternal methylation imprints at imprinting centers (ICs). Dnmt3L, however, lacks the conserved catalytic domain common to DNA methyltransferases. In an attempt to define its function, we coexpressed DNMT3L with each of the two known de novo methyltransfer...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12481029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262443999 |
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