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Site-directed recombination via bifunctional PNA–DNA conjugates
Site-specific DNA binding molecules offer the potential for genetic manipulation of mammalian cells. Peptide nucleic acids (PNAs) are a DNA mimic in which the purine and pyrimidine bases are attached to a polyamide backbone. PNAs bind with high affinity to single-stranded DNA via Watson–Crick base p...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139206/ https://ncbi.nlm.nih.gov/pubmed/12461167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262556899 |
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