The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5′ splice sites
The U1 small nuclear ribonucleoprotein (U1 snRNP) binds to the pre-mRNA 5′ splice site (ss) at early stages of spliceosome assembly. Recruitment of U1 to a class of weak 5′ ss is promoted by binding of the protein TIA-1 to uridine-rich sequences immediately downstream from the 5′ ss. Here we describ...
Zapisane w:
| Wydane w: | EMBO J |
|---|---|
| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2002
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12486009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf668 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|