The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5′ splice sites
The U1 small nuclear ribonucleoprotein (U1 snRNP) binds to the pre-mRNA 5′ splice site (ss) at early stages of spliceosome assembly. Recruitment of U1 to a class of weak 5′ ss is promoted by binding of the protein TIA-1 to uridine-rich sequences immediately downstream from the 5′ ss. Here we describ...
Sparad:
| I publikationen: | EMBO J |
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| Huvudupphov: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Nature Publishing Group
2002
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12486009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf668 |
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