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Secret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutation

A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes.

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Bibliographic Details
Main Author: Maizels, Nancy
Format: Artigo
Language:Inglês
Published: BioMed Central 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC138873/
https://ncbi.nlm.nih.gov/pubmed/11178252
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