Bistability, Stochasticity, and Oscillations in the Mitogen-Activated Protein Kinase Cascade

Signaling pathways respond to stimuli in a variety of ways, depending on the magnitude of the input and the physiological status of the cell. For instance, yeast can respond to pheromone stimulation in either a binary or graded fashion. Here we present single cell transcription data indicating that...

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Hauptverfasser: Wang, Xiao, Hao, Nan, Dohlman, Henrik G., Elston, Timothy C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2006
Schlagworte:
Biophysical Theory and Modeling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386776/
https://ncbi.nlm.nih.gov/pubmed/16361346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073874
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