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Role of BRCA gene dysfunction in breast and ovarian cancer predisposition

Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary breast/ovarian cancer predisposition genes, BRCA1 and BRCA2, appear to participate in a common...

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書目詳細資料
主要作者: Scully, Ralph
格式: Artigo
語言:Inglês
出版: BioMed Central 2000
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC138653/
https://ncbi.nlm.nih.gov/pubmed/11250724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr76
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