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Role of BRCA gene dysfunction in breast and ovarian cancer predisposition

Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary breast/ovarian cancer predisposition genes, BRCA1 and BRCA2, appear to participate in a common...

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Detalles Bibliográficos
Publicado en:Breast Cancer Res
Autor principal: Scully, Ralph
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr76
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