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Role of BRCA gene dysfunction in breast and ovarian cancer predisposition
Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary breast/ovarian cancer predisposition genes, BRCA1 and BRCA2, appear to participate in a common...
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| Formato: | Artigo |
| Idioma: | Inglês |
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BioMed Central
2000
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138653/ https://ncbi.nlm.nih.gov/pubmed/11250724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr76 |
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