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Metallothionein protects against oxidative stress-induced lysosomal destabilization
The introduction of apo-ferritin or the iron chelator DFO (desferrioxamine) conjugated to starch into the lysosomal compartment protects cells against oxidative stress, lysosomal rupture and ensuing apoptosis/necrosis by binding intralysosomal redox-active iron, thus preventing Fenton-type reactions...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1386026/ https://ncbi.nlm.nih.gov/pubmed/16236025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051143 |
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