Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2

Ventricular septal defects are common in human infants, but the genetic programs that control ventricular septation are poorly understood. Here we report that mice with a targeted disruption of the cardiovascular basic helix–loop–helix factor (CHF)1/Hey2 gene show isolated ventricular septal defects...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sakata, Yasuhiko, Kamei, Caramai N., Nakagami, Hironori, Bronson, Roderick, Liao, James K., Chin, Michael T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12454287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252648999
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