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The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery
The low density lipoprotein (LDL) receptor plays a pivotal role in cholesterol metabolism. Inherited mutations that disturb the activity of the receptor lead to elevations in plasma cholesterol levels and early-onset coronary atherosclerosis. Defects in either the LDL receptor or apolipoprotein B, t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138571/ https://ncbi.nlm.nih.gov/pubmed/12451172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252630799 |
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