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The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery

The low density lipoprotein (LDL) receptor plays a pivotal role in cholesterol metabolism. Inherited mutations that disturb the activity of the receptor lead to elevations in plasma cholesterol levels and early-onset coronary atherosclerosis. Defects in either the LDL receptor or apolipoprotein B, t...

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Detalhes bibliográficos
Main Authors: Mishra, Sanjay K., Watkins, Simon C., Traub, Linton M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC138571/
https://ncbi.nlm.nih.gov/pubmed/12451172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252630799
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