Binding of monoclonal antibody to CD16 causes calcium mobilization in large granular lymphocytes but inhibits NK killing.

A monoclonal antibody (mAb), CLB/FcR gran I, reactive with the CD16 Fc receptor (FcRlo/FcRIII) of human cells, leads to calcium mobilization in large granular lymphocytes (LGL) but not in granulocytes. Identical responses are obtained with F(ab')2 fragments of this antibody, indicating that the...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Macintyre, E A, Wallace, D W, O'Flynn, K, Abdul-Gaffar, R, Tetteroo, P A, Morgan, G, Linch, D C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385237/
https://ncbi.nlm.nih.gov/pubmed/2564843
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi