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Killing the umpire: cooperative defects in mitotic checkpoint and BRCA2 genes on the road to transformation
Recent findings from mouse models of BRCA2 genetic lesions have provided intriguing insights and important questions concerning modes of tumor development in familial breast and ovarian cancers. Fibroblasts from mice homozygous for the BRCA2(Tr) allele grow poorly and display an array of chromosomal...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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BioMed Central
1999
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138502/ https://ncbi.nlm.nih.gov/pubmed/11250674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr4 |
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