Agalactosyl IgG and beta-1,4-galactosyltransferase gene expression in rheumatoid arthritis patients and in the arthritis-prone MRL lpr/lpr mouse.

Reduced galactosylation of immunoglobulin G (IgG) is well documented in rheumatoid arthritis (RA), but the reason for this defect is still unknown. There is some evidence supporting a defect in the biosynthetic pathway, and a reduction in the level of beta-1,4-galactosyltransferase (beta-1,4-GalTase...

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Detalhes bibliográficos
Main Authors: Jeddi, P A, Bodman-Smith, K B, Lund, T, Lydyard, P M, Mengle-Gaw, L, Isenberg, D A, Youinou, P, Delves, P J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384147/
https://ncbi.nlm.nih.gov/pubmed/8675223
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