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T-cell dependent response to immune complexes abrogates B-cell unresponsiveness to pneumococcal cell wall polysaccharide.
Although > 90% of B cells from M167 (mu, kappa) immunoglobulin transgenic (Tg) mice express surface immunoglobulin that binds phosphorylcholine (PC), we found that these mice are unresponsive to immunization with pneumococcal cell wall polysaccharide (PnC), a type II thymus-independent antigen th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383933/ https://ncbi.nlm.nih.gov/pubmed/8550067 |
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