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T-cell dependent response to immune complexes abrogates B-cell unresponsiveness to pneumococcal cell wall polysaccharide.

Although > 90% of B cells from M167 (mu, kappa) immunoglobulin transgenic (Tg) mice express surface immunoglobulin that binds phosphorylcholine (PC), we found that these mice are unresponsive to immunization with pneumococcal cell wall polysaccharide (PnC), a type II thymus-independent antigen th...

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Bibliografiske detaljer
Main Authors: Caulfield, M J, Stanko, D
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383933/
https://ncbi.nlm.nih.gov/pubmed/8550067
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