Serotype-Specific and Age-Dependent Generation of Pneumococcal Polysaccharide-Specific Memory B-Cell and Antibody Responses to Immunization with a Pneumococcal Conjugate Vaccine

Glycoconjugate vaccines have dramatically reduced the incidence of encapsulated bacterial diseases in toddlers under 2 years of age, but vaccine-induced antibody levels in this age group wane rapidly. We immunized adults and 12-month-old toddlers with heptavalent pneumococcal conjugate vaccine to de...

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Detalhes bibliográficos
Main Authors: Clutterbuck, Elizabeth A., Oh, Sarah, Hamaluba, Mainga, Westcar, Sharon, Beverley, Peter C. L., Pollard, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238039/
https://ncbi.nlm.nih.gov/pubmed/18032593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00336-07
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