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Class II phosphoinositide 3-kinase α-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle
We demonstrated previously that membrane depolarization and excitatory receptor agonists such as noradrenaline induce Ca(2+)-dependent Rho activation in VSM (vascular smooth muscle), resulting in MP (myosin phosphatase) inhibition through the mechanisms involving Rho kinase-mediated phosphorylation...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383708/ https://ncbi.nlm.nih.gov/pubmed/16336212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051471 |
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