Class II phosphoinositide 3-kinase α-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle

We demonstrated previously that membrane depolarization and excitatory receptor agonists such as noradrenaline induce Ca(2+)-dependent Rho activation in VSM (vascular smooth muscle), resulting in MP (myosin phosphatase) inhibition through the mechanisms involving Rho kinase-mediated phosphorylation...

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Hlavní autoři: Wang, Yu, Yoshioka, Kazuaki, Azam, Mohammed Ali, Takuwa, Noriko, Sakurada, Sotaro, Kayaba, Yuji, Sugimoto, Naotoshi, Inoki, Isao, Kimura, Takaharu, Kuwaki, Tomoyuki, Takuwa, Yoh
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383708/
https://ncbi.nlm.nih.gov/pubmed/16336212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051471
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