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Transferrin receptor-like proteins control the degradation of a yeast metal transporter

Plasma membrane transporters are often downregulated by their substrates. The yeast manganese transporter Smf1 is subject to two levels of regulation: heavy metals induce its sequestration within the cell, and also its ubiquitination and degradation in the vacuole. Degradation requires Bsd2, a membr...

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Bibliographic Details
Main Authors: Stimpson, Helen E M, Lewis, Michael J, Pelham, Hugh R B
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383565/
https://ncbi.nlm.nih.gov/pubmed/16456538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600984
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