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Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20
Fertilizable mammalian oocytes are arrested at the second meiotic metaphase (mII) by the cyclinB-Cdc2 heterodimer, maturation promoting factor (MPF). MPF is stabilized via the activity of an unidentified cytostatic factor (CSF), thereby suspending meiotic progression until fertilization. We here pre...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383546/ https://ncbi.nlm.nih.gov/pubmed/16456547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600953 |
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